In the H2020 Health call on In-Silico Clinical Trials, Prof. Alfons Hoekstra has received a grant as partner in the INSIST project: IN Silico trials for treatment of acute Ischemic STroke. The main goal of INSIST is to realize in silico clinical stroke trials for biomedical products for treatment of acute ischemic stroke. Such an in silico clinical ischemic stroke trial consists of the generation of populations of virtual stroke patients, in silico models of treatments, and in silico models of the biophysiological aspects of the human response to stroke.

Hoekstra’s team at the Computational Science Lab will work on multiscale models for thrombolysis, for brain tissue perfusion and on computational environments for in-silico clinical trials.