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Virolab


Virolab

The HIV virus genome consists of only 9 genes that code for 19 proteins. The complexity of HIV infection and virus reproduction in the human host is a result of the multitude of interactions that HIV has with its host. Many of these interactions have been studied on a protein level and can be collected in a so called protein interaction network where these 19 HIV proteins interact with thousands of human proteins. Visualization and analysis of this complex network using a graph-theoretic approach can bring new insight into the workings of the HIV virus and its relation to the human host. Where classical biology looks at individual interactions, in complex systems we study the system as a whole. Using this integrated approach and with the help of state-of-the-art computational techniques we envisage today what biological and medical research will be like in the future.

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Virolab



EU IST STREP Project027446

http://www.virolab.org/


Prof. Dr Peter Sloot
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