Peridynamics

Peridynamics is a particle-based formulation of structural mechanics, and is a good candidate to bridge the scales from the cellular level to the tissue level in multiscale models of soft biological tissues. In this project you will investigate this idea by formulation a Peridynamics model for vascular tissue, implementing it using a public domain parallel molecular dynamics package, and tune the model to reproduce vascular tissue mechanics. Once validated, your model will then serve to build a multiscale model of a tissue, where the langrangian particles in the Peridynamics model are turned into agents, mimicking the proliferative behaviour of real cells.